Skip to main content
. 2007 Nov;56(11):1625–1634. doi: 10.1136/gut.2006.112110

Table 3 Indications and contraindications for endoscopic resection in early squamous cell and Barrett's cancer.

Indication for ER Intermediate indication* Contraindication for ER
Barrett's neoplasia LGIN, HGIN, carcinoma, size <20 mm, no risk factors, macroscopic type I, IIa, b, c Adenocarcinoma >20 mm, multifocal adenocarcinoma, sm1 infiltration without risk factors Sm2 tumour infiltration and deeper, sm1 cancer with one risk factor, macroscopic type III
Squamous cell neoplasia LGIN, HGIN, mucosal cancer, no risk factors, macroscopic type I, IIa, b, c Size >20 mm, multifocal cancer Sm1 cancer and deeper, macroscopic type III

LGIN, Low‐grade intraepithelial neoplasia; HGIN, high‐grade intraepithelial neoplasia.

*Endoscopic resection (ER) should only be performed in highly experienced centres or under study conditions.

Risk factors: lymph vessel invasion (L1), venous infiltration (V1), poorly differentiated carcinoma (G3).