Table 2 Distribution of clinical characteristics at time of transplantation in the UK and Ireland and the USA between 1 March 1994 and 31 March 2005.
| Overall | Acute liver failure | Chronic liver disease | ||||
|---|---|---|---|---|---|---|
| Characteristic | UK and Ireland | USA | UK and Ireland | USA | UK and Ireland | USA |
| Number of recipients | 5925 | 41 866 | 773 | 1507 | 5152 | 40 359 |
| Recipient age (years) | 48.6 (12.5) | 50.4 (10.8) | 36.5 (13.2) | 38.5 (14.1) | 50.4 (11.4) | 50.8 (10.4) |
| Recipient gender (% male) | 56.1 | 63.2 | 33.0 | 33.1 | 59.6 | 64.3 |
| Recipient race (%) | ||||||
| White | 86.3 | 87.0 | 87.3 | 71.3 | 86.1 | 87.6 |
| Non‐white | 13.7 | 13.0 | 12.7 | 28.7 | 13.9 | 12.4 |
| Recipient BMI (kg/m2) | 25.4 (4.9) | 27.7 (5.8) | 24.3 (5.0) | 26.8 (6.3) | 25.5 (4.9) | 27.7 (5.8) |
| Albumin (g/dl) | 3.0 (0.7) | 2.9 (0.7) | 2.8 (0.9) | 2.8 (0.6) | 3.0 (0.6) | 2.9 (0.7) |
| Bilirubin (mg/dl) | 7.5 (9.6) | 6.8 (9.6) | 17.0 (12.5) | 20.1 (12.5) | 6.1 (8.2) | 6.3 (9.1) |
| Creatinine (mg/dl) | 1.5 (1.2) | 1.3 (1.1) | 2.8 (1.6) | 2.2 (1.9) | 1.3 (0.9) | 1.3 (1.0) |
| Calculated MELD score | 20.2 (11.0) | 19.5 (9.6) | 39.8 (9.6) | 35.0 (9.0) | 17.3 (7.9) | 19.0 (9.1) |
| Preoperative renal support (%) | 12.8 | 4.2 | 50.3 | 17.1 | 7.2 | 3.7 |
| Preoperative ventilation (%) | 11.0 | 5.9 | 73.7 | 52.4 | 1.6 | 4.1 |
| Previous upper abdominal surgery (%) | 18.3 | 35.8 | 8.1 | 18.8 | 19.9 | 36.3 |
| Graft type (%) | ||||||
| Whole | 94.4 | 94.4 | 91.6 | 96.6 | 94.9 | 94.4 |
| Segmental | 5.6 | 5.6 | 8.4 | 3.4 | 5.1 | 5.6 |
| Cold ischaemic time (min) | 658.1 (190.1) | 497.3 (240.7) | 601.0 (190.1) | 486.6 (242.2) | 666.8 (188.6) | 497.7 (240.6) |
| Donor age (years) | 42.7 (15.0) | 38.4 (17.4) | 41.7 (15.6) | 36.9 (17.7) | 42.8 (14.9) | 38.5 (17.4) |
| Donor type (%) | ||||||
| Cadaveric heart‐beating | 98.6 | 94.6 | 99.9 | 97.8 | 98.5 | 94.4 |
| Living | 0.4 | 4.1 | 0 | 1.1 | 0.4 | 4.2 |
| Cadaveric non‐heart‐beating | 1.0 | 1.3 | 0.1 | 1.1 | 1.1 | 1.4 |
| Donor cause of death (%) | ||||||
| Trauma | 21.1 | 45.1 | 20.8 | 44.6 | 21.1 | 45.1 |
| Cerebrovascular accident | 64.5 | 42.9 | 65.7 | 42.7 | 64.4 | 42.9 |
| Cerebral anoxia | 6.7 | 9.1 | 6.8 | 9.5 | 6.7 | 9.1 |
| Other | 7.7 | 2.9 | 6.7 | 3.2 | 7.8 | 2.9 |
| Donor BMI (kg/m2) | 24.8 (4.3) | 25.4 (5.8) | 24.3 (4.0) | 25.1 (5.9) | 24.9 (4.3) | 25.5 (5.8) |
| Donor–recipient gender match (%) | ||||||
| Male–male | 35.3 | 40.6 | 18.4 | 20.3 | 37.8 | 41.3 |
| Female–male | 20.8 | 22.5 | 14.6 | 12.7 | 21.8 | 22.9 |
| Male–female | 18.2 | 19.1 | 31.8 | 37.7 | 16.2 | 18.4 |
| Female–female | 25.7 | 17.8 | 35.2 | 29.3 | 24.2 | 17.4 |
| Donor–recipient blood group match (%) | ||||||
| Identical | 89.8 | 91.7 | 67.0 | 66.6 | 93.2 | 92.6 |
| Compatible | 9.7 | 7.4 | 32.3 | 27.9 | 6.3 | 6.7 |
| Incompatible | 0.5 | 0.9 | 0.7 | 5.5 | 0.5 | 0.7 |
| Donor–recipient CMV match (%) | ||||||
| Positive match | 64.2 | 68.2 | 52.2 | 71.1 | 65.7 | 68.0 |
| Positive mismatch | 17.7 | 18.9 | 24.8 | 16.4 | 16.8 | 19.0 |
| Negative match | 18.1 | 12.9 | 23.0 | 12.5 | 17.5 | 13.0 |
| Re‐transplantation requirement (%) | 9.0 | 8.0 | 10.7 | 9.3 | 8.7 | 8.0 |
| Annual transplant centre volume | 95.5 (38.7) | 67.7 (46.9) | 96.9 (41.0) | 68.7 (50.3) | 95.3 (38.3) | 67.7 (46.8) |
Values are means (SD) unless indicated as percentages.
BMI, body mass index; CMV, cytomegalovirus; MELD, model for end‐stage liver disease.