Figure 3 Correlation of faecal S100A12 and faecal calprotectin with disease location. In patients with active inflammatory bowel disease (IBD), the test for faecal S100A12 performs equally well regardless of disease location. The analysis of variance revealed no significant differences, although there was a trend towards higher levels of distal inflammation compared with more proximal inflammation. Faecal S100A12 seems to be a more robust test in this regard than faecal calprotectin (L, left; R, right; Others, proctitis and isolated sigma inflammation).