Figure 2 Bone marrow derived cells (BMDCs) isolated from green fluorescent protein (GFP) positive rats acquire morphological features and phenotypic markers of differentiated hepatocytes after transplantation into liver injured Lewis recipients (group D). Serial sections of livers removed 72 hours after cell transplantation were stained for GFP (A) (C) and for CK‐18 (B) (D). GFP positive cells are also positive for the epithelial marker CK‐18. Several GFP positive cells with hepatocyte‐like morphology are visible. The arrow indicates a binucleated cell, a feature typical of hepatocytes. Some GFP positive cells are smaller and have smaller nuclei (arrowheads) than the surrounding host hepatocytes. (Original magnification ×40.) The two figures in the lower panel are: (E) a liver section from a Lewis rat (group E, GFP negative control) and (F) a liver section from a GFP‐transgenic animal (GFP positive control), respectively. (Original magnification ×10.)