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. 2007 Jul 19;56(12):1725–1735. doi: 10.1136/gut.2007.127969

graphic file with name gt127969.f5.jpg

Figure 5 Bone marrow derived cells (BMDCs) isolated from green fluorescent protein (GFP) positive transgenic rats acquire morphological features and phenotypic markers of differentiated hepatocytes after transplantation into liver injured Lewis recipients (group F). Serial sections of livers removed four weeks after cell transplantation were stained for GFP (A) and for CK‐18 (B). (C–E) Extensive repopulation of liver parenchyma with GFP positive hepatocyte‐like cells four weeks after transplantation of 10×106 GFP positive BMDCs (group F). Large clusters of GFP positive hepatocyte‐like cells are mainly located in proximity of blood vessels. (F) GFP positive endothelial‐like cells (arrows) are also visible in the ischaemic lobes. (Original magnification: (A), (B) ×20; (C), (D), (E) ×10; (F) ×40.)