Table 1 Summary of experimental groups.
| Group | Procedure | Harvest | n | ||
|---|---|---|---|---|---|
| Cell tracking with fluorescent dye | Transplantation of fluorescent labelled BMDCs (PKH26) | ||||
| A | 5×106 BMDCs ip in the absence of I/R injury | 72 h | 9 | ||
| B | 5×106 BMDCs ip after I/R injury | 72 h | 16 | ||
| C | Vehicle only after I/R injury | 72 h | 6 | ||
| Cell tracking with GFP and Y chromosome | Transplantation of GFP positive BMDCs | ||||
| D | 7×106 BMDCs after I/R injury | 72 h | 5 | ||
| E | vehicle only after I/R injury | 72 h | 3 | ||
| F | 1×106, 7×106, and 10×106 BMDCs after I/R injury | 1 m | 7 | ||
| G | Vehicle only after I/R injury | 1 m | 6 | ||
| Investigating cell fusion | Transplantation of BMDCs from wild type into GFP positive rats | ||||
| H | 7×106 BMDCs after I/R injury | 1 m | 6 | ||
| I | Vehicle only after I/R injury | 1 m | 4 | ||
| Assessing liver specific metabolic function in vivo | Transplantation of BMDCs from wild type into Gunn rats | ||||
| K | 10×106 BMDCs after I/R injury | 1 m | 6 | ||
| L | Vehicle only after I/R injury | 1 m | 6 |
BMDC, bone marrow derived cell; GFP, green fluorescent protein; ip, intraportal; I/R, ischaemia/reperfusion.