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. 2007 Jul 25;56(12):1743–1746. doi: 10.1136/gut.2006.099226

Table 2 Selection of patients for validation of the Glasgow alcoholic hepatitis score.

Hospital site No. of patients: total (NT; CS) Dates of recruitment Inclusion/exclusion criteria Indications for corticosteroids
Glasgow 38 (8; 30) 2002–3 GI bleeders excluded CS used if sepsis excluded or adequately treated; mDF ⩾32
Birmingham 25 (19; 6) 2002–3 GI bleeders excluded CS used if sepsis excluded or adequately treated; mDF ⩾32
Newcastle 65 (29; 36) 2000–3 Part of an RCT comparing antioxidants with placebo; mDF ⩾32 CS used if no active infection or GI bleeding
London 82 (38; 44) 1997–2001 RCT comparing antioxidants with CS; mDF ⩾32; serum bilirubin >100 μmol/l, serum creatinine <500 μmol/l. No active sepsis or GI bleeding for 48 hours Randomised as part of RCT
Dudley 15 (14; 1) 2001–3 Patients with recent GI bleeding included CS not used routinely

CS, Corticosteroids (40 mg prednisolone for 4 weeks except for London where 30 mg was given for 4 weeks); GI, gastrointestinal; mDF, modified Maddrey's discriminant factor; NT, not treated; RCT, randomised controlled trial; All patients had a serum bilirubin ⩾80 μmol/l, a history of recent alcohol excess and aspartate aminotransferase level <500 IU/l.