Table 2.
Functional classification of the top 10% deadenylated mRNAs
| Initiation factors (7) |
| Eif2s2, Eif3s4, Eif3s7, Eif3s9, Eif4b, Eif4e2, Eif4g2 |
| Initiation factor associated proteins(2) |
| Eif4ebp2, Eif3s6ip |
| Aminoacyl-tRNA-synthetases (3) |
| Aars, Eprs, Yars |
| Other RNP proteins (18) |
| Cdc5l, Csda, Cugbp2, Ddx21, Ddx24, Eif2c2, Hdlbp, Heatr1, Larp5, Mrto4, Nol5, Npm3, Serbp1, Sf3b2, Srp72, Tcof1, Tnpo3, Tsn |
| Cell adhesion and actin cytoskeleton (13) |
| AA536749 (p116Rip), Actn4, Adrm1, Basp1, C920006C10Rik, Cald1, Capzb, Cdc42, Cdh2, Mapkapk2, Mapre1, Tm4sf1,Tpbg |
| Cell cycle (10) |
| Aurkb, Calm1, Ccnd2, Ccnd3, Cdc42, Cdc5l, Mad2l1bp, Nubp1, Nuf2, Tbrg1 |
| Chromatin components and transcription factors (19) |
| Actl6a, Cebpa, Ercc1, Ercc5, Gins4, Hist1h3e, Hist1h4c, Hist1h4d, Hmga1, Msh6, Nfic, Pold2, Rnf4, Rpo1-1, Snd1, Sssca1, Tcf25, Tsn, Whsc1 |
| Ubiquitination, proteasome and associated proteins (11) |
| Adrm1, Cct5, Cops4, Psmc5, Psmd1, Psmd11, Rnf26, Rnf4, Sqstm1, Trip12, Ube2r2 |
| Endoplasmatic reticulum, golgi and lysosomes (14) |
| Ap3b1, Ccdc115, Cdipt, Elovl6, Foxred2, Gorasp2, Ift20, Mtmr4, Pigc, Sec63, Srp72, Stt3b, Tmed5, Tmed8 |
| Other mRNAs (47) |
| 1200011I18Rik, 1600014C10Rik, 2210412D01Rik, 2510006D16Rik, 2810026P18Rik, 4921533L14Rik, Acaa2, Alad, Armcx2, Asnsd1, Aven, C030045D06Rik, Comt, Csnk2b, D15Wsu75e, Ddah1, Drg1, Dtl, EG622339, Ext1, Frrs1, Gcat, Gdap1, Gpiap1, Grina, Hdgf, |
| Hsp90aa1, Il6st, Irgq, Lap3, Lrrc17, Mark2, Muc5ac, Neat2, Neat2, Pex13, Sh3d19, Spred1, Thop1, Tmprss2, Tomm22, Tspan31, Ttc1, Txndc9, Wbp5, Zfp606 |
The non-cross-hybridizing top 10% of deadenylated mRNAs (148 probes) were put into functional categories as indicated. This table is an extract of Supplementary Table 3.