Figure 4.

Overall conformation of RNA dodecamer duplexes with rF:G pairs. (A) One of the two RNA duplexes (duplex 1) per crystallographic asymmetric unit viewed into the major groove. Carbon atoms of the F moiety are highlighted in magenta and fluorine atoms are shown as green spheres. (B) Superimposition of the two duplexes; duplex 1 is red and duplex 2 is blue. (C) Overall conformation of the RNA dodecamer duplex with A:G pairs; the view is into the major groove that contains four Mg²⁺ hexahydrate complexes.