Table 3.
Genotype frequencies and risk of prostate cancer.
| UGT2B17 genotypea | Cases (%) | Controls (%) | OR (95% CI)b |
|---|---|---|---|
| (+/+) | 201 (49) | 190 (48) | 1.00 (Ref.) |
| (+/0) | 168 (41) | 159 (40) | 0.99 (0.73–1.35) |
| (0/0) | 42 (10) | 48 (12) | 0.89 (0.55–1.45) |
| (+/+) | 201 (49) | 190 (48) | 1.00 (Ref.) |
| (+/0) + (0/0) | 210 (51) | 207 (52) | 0.97 (0.73–1.30) |
| (+/+) + (+/0) | 369 (90) | 349 (88) | 1.00 (Ref.) |
| (0/0) | 42 (10) | 48 (12) | 0.89 (0.56–1.43) |
The three genotypes of the UGT2B17 deletion polymorphism are shown as: (+/+), two alleles of the UGT2B17 gene; (+/0), one allele of the UGT2B17 gene and one gene deletion allele; (0/0), UGT2B17 null, two copies of the deletion allele.
Adjusted for age, smoking pack-years, and family history of prostate cancer.