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. Author manuscript; available in PMC: 2008 Oct 1.
Published in final edited form as: Brain Res Rev. 2007 Feb 6;55(2):220–227. doi: 10.1016/j.brainresrev.2007.01.012

Fig. 3.

Fig. 3

MARCM-based mutant analysis using loss-of-function mutants, misexpression, or both revealed regulation of axon terminal arborization of olfactory projection neurons by POU domain transcription factor Acj6. The axon arborization pattern of DL1 single cell clones in (A) wild type, (B) acj6−/−, (C) rescue: acj6−/−+ UAS-Acj6, and (D) acj6−/− + UAS-Dfr are shown. The characteristic dorsal branch is substantially shorter in the acj6−/− clone; this is rescued by acj6 transgene expression (arrowheads). Expression of a different POU domain transcription factor Drifter (dfr) in DL1 gives rise to a novel axon terminal arborization pattern (arrow in D). Modified after Komiyama et al. (2003).