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Intracellular molecules candidates for the role of constitutive danger signals.
| Ligand (danger signal) | Receptor (danger sensor) |
|---|---|
| Heat shock proteins (HSP60, HSP70, HSP90) | CD91, TLR4, TLR4/TLR2, LOX-1 |
| Uric acid crystals | ? |
| DNA | TLR9 |
| ssRNA | TLR3, TLR7, TLR8 |
| Nucleotides | P2Y11,2,4,6,11, P2X4,7 |
| Sugar metabolites | P2Y14 |
| (UDPglucose) |
