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. 2005 Dec 3;1(4):349–358. doi: 10.1007/s11302-005-8076-x

Table 3.

Ki values for NTPDase1, 2 and 3 obtained for reactive blue 2, PPADS, suramin, and ARL67156, using the in-capillary electrophoresis method.

Inhibitora Ki ± SEM [μM]
NTPDase1 NTPDase2 NTPDase3
RB2 20.0 ± 0.003 24.2 ± 0.06 1.10 ± 0.03
PPADS 46.0 ± 0.01 44.2 ± 0.03 3.0 ± 0.001
Suramin 300 ± 0.1 65.4 ± 0.01 12.7 ± 0.03
ARL 67156 27.0 ± 0.004 Q 1000b 112.1 ± 0.05
Dipyridamole > 1000c > 1000c > 1000c

The results are means T SEM of three separate experiments each run in duplicate.

a For structures see Figure 1.

b50% inhibition at 1 mM concentration.

cNo inhibitory activity up to a concentration of 1 mM.