Table 3.
Inhibitora | Ki ± SEM [μM] | ||
---|---|---|---|
NTPDase1 | NTPDase2 | NTPDase3 | |
RB2 | 20.0 ± 0.003 | 24.2 ± 0.06 | 1.10 ± 0.03 |
PPADS | 46.0 ± 0.01 | 44.2 ± 0.03 | 3.0 ± 0.001 |
Suramin | 300 ± 0.1 | 65.4 ± 0.01 | 12.7 ± 0.03 |
ARL 67156 | 27.0 ± 0.004 | Q 1000b | 112.1 ± 0.05 |
Dipyridamole | > 1000c | > 1000c | > 1000c |
The results are means T SEM of three separate experiments each run in duplicate.
a For structures see Figure 1.
b50% inhibition at 1 mM concentration.
cNo inhibitory activity up to a concentration of 1 mM.