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. 2007 Feb 27;107(1):41–47. doi: 10.1007/s10549-007-9534-7

Table 2.

Mean percentage of FANCD2-positive cells in high- and low-level expression groups of hormone receptors, growth factor receptors, Cyclin D1, and p53 in sporadic and hereditary breast cancers

Number (%) Mean (SE) of FANCD2% p Value (t test)
Total 117 (100)
ER
   Low 56 (48) 14 (2.5) 0.019
   High 61 (52) 8 (1.6)
PR
   Low 81 (69) 17 (1.9) 0.016
   High 36 (31) 12 (1.9)
HER-2/neu
   Negative 93 (79) 16 (1.6) 0.797
   Positive 24 (21) 17 (3.5)
EGF receptor
   Negative 78 (66) 13 (1.5) 0.002
   Positive 39 (33) 19 (3.1)
Cyclin D1
   Low 85 (73) 12 (1.9) 0.002
   High 32 (27) 7 (2.6)
p53
   Low 88 (75) 8 (1.3) <0.001
   High 29 (25) 19 (4.3)

ER estrogen receptor, PR progesterone receptor