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Dominant negative PKR and eIF2α-51A confer resistance to CLT. NIH 3T3 cell were transfected with pBABE, wild type (WT) or eIF2α-51A (A and B), or dominant negative PKR (C and D). Selected clones were tested for resistance to CLT by [3H]thymidine incorporation (A and C) or by 35S-Met-Cys incorporation (B and D).
