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. Author manuscript; available in PMC: 2007 Nov 28.
Published in final edited form as: J Biol Chem. 2006 Apr 28;281(26):18081–18089. doi: 10.1074/jbc.M513640200

FIGURE 5. KOR-mediated p38 activation in AtT-20 cells and Striatal Astrocytes is concentration-dependent.

FIGURE 5

A, phospho-p38 MAPK (P-p38) concentration-response curves for the KOR agonists U50,488 and the endogenous KOR agonist-peptide dynorphin B in AtT-20 cells expressing KOR-GFP. B, phospho-p38 concentration-response curves for the KOR agonists U50,488 and salvinorin A in primary striatal astrocytes. All agonist treatments were performed at the 15-min time point. n = 3– 4, with each n taken from a separate cell culture and experiment.