FIGURE 6. BEL or genetic deletion of iPLA2β abolishes PGF2α-induced RGS2 mRNA up-regulation in VSMC.
Prior to PGF2α stimulation (30μm, 1 h), wild-type cells (A), but not iPLA2β-null cells (B), were preincubated with different concentrations of BEL. The RGS2 mRNA expression was determined by real-time PCR. The summary data are from at least seven independent experiments. ###, p < 0.001 versus basal; ***, p < 0.001 versus PGF2α stimulation alone; **, p < 0.01 versus basal.