Table 4.
Deletions and insertions in hprt mutants of RAW264.7 cells stimulated to produce NO
| Position | Mutation | Surrounding sequence |
|---|---|---|
| Stimulation with IFN-γ, 23 days | ||
| 132 | −C | GAA(C)AGG |
| 503 or 504 | −C | GGA(C)(C)TCT |
| 526 or 527 | −C | AGG(C)(C)AGA |
| 643-646 | −4 bp | |
| 610-626 | −17 bp | |
| 610-626 | −17 bp | |
| 160-230 | −71 bp | |
| 207-212 | +G | GGGGGG |
| exons 4-6 | duplication | |
| exon 2 | replaced by a 116-bp fragment | |
| Stimulation with LPS + IFN-γ, 4 days | ||
| −22 to 2 | 24-bp deletion | |
| 503 or 504 | −C | GGA(C)(C)TCT |
| 532, 533, or 534 | −T | AGAC(T)TTG |
| 606, 607 | 7-bp insertion | |