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. 1998 Jul 7;95(14):8369–8374. doi: 10.1073/pnas.95.14.8369

Table 2.

Reversal of resistance to taxol in CCRF-CEM/VBL100 cells by NAA

Treatment CCRF-CEM CCRF-CEM/VBL100, IC50 in μ Ratio
Taxol only 0.0011 (A) 1.51 (C) (C)/(A) = 1372
±0.0015 ±0.30
Taxol with 0.00048 (B) 0.0018 (D) (D)/(B) = 3.8
 10 μm NAA ±0.000004 ±0.0001
Ratio (A)/(B) = 2.3* (C)/(D) = 839*

The IC50 values for taxol were determined with the median-effect plots using a computer (23, 24). The taxol was varied at 6-7 concentrations. Mean ± 95% confidence intervals are shown. 

*

Fold of enhancement of taxol effect by 10 μM of NAA. 

Fold of resistance to taxol in CCRF-CEM/VBL100 cells.