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Effects of glibenclamide (○) and α-endosulfine (•) on [3H]glibenclamide binding to MIN6 cell membranes. Half-maximal inhibition of [3H]glibenclamide binding was produced by 1nM glibenclamide and 1 μM endosulfine. Each point is the mean of duplicate determinations within a representative experiment, which has been reproduced 3-fold.
