Comparison between finite and classic (infinite chain) WLC solutions. (A) Persistence length determined by fitting experimental data to the classic WLC solution (pwlc, red) and the finite WLC solution using half-constrained boundary conditions (pfin, blue) as a function of DNA length. (B) Fractional error in the fitted p from p∞ showing an approximately threefold reduction in the length dependence of pfin as compared to pwlc. Ideally, p, an intrinsic property of the molecule, would be independent of L. Error bars represent the standard error of the mean.