TABLE 1.

Predicted parameters of apoMb_1-29 aggregation

Variant	Sequence	Zagg*	Sagg†	‡
WT	GLSDGEWQQVLNVWGKVEADIAGHGQEVL	0.37	0.59	0.625
P1	GLSDGEWQQVENVWGKVEADIAGHGQLVL	0.37	0.00	0.624
P2	GLSDGEWQQVLENVWGKVEADIAGHGQVL	0.37	0.32	0.607
P3	GLSDGEQQVLWINVWGKVEADAGHGQEVL	0.37	4.15	0.683
P4	GLSDGEQQVLVWIVNVWGKEADAGHGQEL	0.37	7.74	0.941

^*Aggregation Z-score of the entire sequence, calculated as described in Materials and Methods, and previously (18).

^†Prominence of the aggregation promoting region, calculated as described in Materials and Methods.

^‡New aggregation Z-score, calculated as described in Materials and Methods.