TABLE 1.

Kinetic constants for the association of DHE with lipid bilayer membranes at 288 and 308 K

	POPC		POPC-Chol (1:1)		SpM-Chol (6:4)
	288 K	308 K	288 K	308 K	288 K	308 K
k+ (M−1 s−1)	4.8 ± 0.4 × 106	5.1 ± 0.5 × 107	6.3 ± 0.6 × 106	6.4 ± 0.6 × 107	6.3 ± 0.5 × 105	1.3 ± 0.1 × 107
k− (s−1)	4.7 ± 1.1 × 10−5	1.0 ± 0.2 × 10−3	4.5 ± 1.4 × 10−5	6.4 ± 2.1 × 10−4	1.4 ± 0.4 × 10−5	6.9 ± 2.1 × 10−5
KL (M−1)	1.0 ± 0.2 × 1011	5.1 ± 1.1 × 1010	1.4 ± 0.4 × 1011	1.0 ± 0.3 × 1011	4.6 ± 1.3 × 1010	1.9 ± 0.6 × 1011
KP(L/W)	2.6 × 106	1.3 × 106	3.6 × 106	2.5 × 106	1.2 × 106	4.8 × 106