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. 2007 Aug 31;93(12):4244–4253. doi: 10.1529/biophysj.107.112847

TABLE 4.

Some reported rate constants for exchange of sterols between lipid bilayer (donors) and other lipid bilayers or cyclodextrin (acceptors)

Exchanged molecule Donor membrane Acceptor membrane kexchange (s−1) T (K) Reference
Cholesterol Erythrocyte ghosts eggPC, SUV 1.3 × 10−5 319 (19)
PC-Chol-dicetylphosphate (65:20:15); SUV PC-Chol (80:20); SUV 8.9 × 10−5 310 (20)
eggPC-Chol (90:10); SUV eggPC-Chol (90:10); SUV 1.6 × 10−4 310 (21)
eggPC-Chol (94:6); SUV eggPC-Chol (94:6); SUV 6.6 × 10−5 310 (22)
eggPC-Chol (94:6); SUV eggPC-Chol (94:6); LUV 7.5 × 10−5 310
eggPC-Chol (94:6); LUV eggPC-Chol (94:6); SUV 3.5 × 10−5 310
eggPC-Chol (94:6); LUV eggPC-Chol (94:6); LUV 3.6 × 10−5 310
SpM-Chol (1:1); SUV Rat liver microsomes 6.8 × 10−6 310 (23)
PC-Chol (1:1); SUV Rat liver microsomes 7.5 × 10−5 310
POPC-Chol (99:1); SUV POPC-Chol (99:1); SUV 2.5 × 10−4 310 (24)
POPC-Chol (90:10); SUV POPC-Chol (90:10); SUV 1.6 × 10−4 310
POPC-Chol (80:20); SUV POPC-Chol (80:20); SUV 1.3 × 10−4 310
eggPC-Chol-Cerebroside (75:10:15); SUV eggPC; LUV 1.2 × 10−4 310 (12)
eggPC-Chol-Cerebroside (75:10:15); LUV eggPC; LUV 5.0 × 10−5 310
eggPC-Chol-Cerebroside (75:10:15); MLV eggPC; LUV 1.6 × 10−5 310
DPPC-POPG-Chol (80:15:5); LUV Cyclodextrin 2.5 × 10−2 (78%) 310 (25)
5.3 × 10−5 (22%)
CHO-K1 cells Cyclodextrin 4.6 × 10−2 (25%) 310 (26)
5.5 × 10−4 (75%)
DHE POPC-DHE (65:35); SUV POPC-DHE (65:35) 3.6 × 10−4 (12.5%) 297 (6)
4.9 × 10−5 (87.5%)
POPC-DHE (99:1); SUV POPC-POPG (85:15); SUV 7.7 × 10−4 298 (27)
4.3 × 10−4
POPC-DHE (65:35); SUV POPC-DHE (65:35); SUV 3.9 × 10−4 (36%) 310 (8)
1.0 × 10−4 (64%)
POPC; SUV Cyclodextrin 2.6 × 10−1 283 (45)
POPC; LUV Cyclodextrin 1.7 × 10−1 283