Skip to main content
. Author manuscript; available in PMC: 2008 Sep 1.
Published in final edited form as: Mech Dev. 2007 Jul 19;124(9-10):657–667. doi: 10.1016/j.mod.2007.07.005

Figure 4. Activation of PI3K or Erk MAPK rescued convergent extension of DMZ explants from ErbB4 morphant embryos.

Figure 4

Coexpression of 5-10pg mRNA/embryo of p110caax or MEK* rescued elongation of the DMZ explants from ErbB4 morphant embryos (20ng ErbB4-MO/embryo) at mid-neurula (stage 18) and tailbud (stage 24) stages. At tailbud stages, explants from ErbB4-MO injected embryos started to dissociate, and p110caax prevented cell shedding more efficiently than MEK* did.