FIG. 6.

Deletion of the histone methyltransferase genes suppresses the H3 K4,36,79R lethal phenotype. (A) Growth ability of the set1Δ set2Δ dot1Δ mutant strain. (B and C) Histone H3 mutant strains lacking Set1 methyltransferase were transformed with the wild-type SET1 or different set1 mutant alleles and then tested for viability, as shown in Fig. 1A.