Table 4.
Haplotype-based association with antisocial alcohol dependence.
| Block | Haplotype | Control (N=287) | AD (N=222) | Global P | P* | Corrected P |
|---|---|---|---|---|---|---|
| 1A | 112222111122212111 | 0.604 | 0.527 | 0.057 | 0.013 | 0.065 |
| 1B | 111211211112112111 | 0.127 | 0.141 | |||
| 1C | 211111211112121221 | 0.099 | 0.129 | |||
| 1D | 112222211112121221 | 0.046 | 0.026 | |||
| 1E | 112222111112121221 | 0.037 | 0.037 | |||
| 2A | 11221 | 0.485 | 0.512 | |||
| 2B | 11212 | 0.237 | 0.181 | 0.944 | 0.034 | 0.170 |
| 2C | 22112 | 0.161 | 0.214 | |||
| 2D | 21212 | 0.046 | 0.036 | |||
| 2E | 12112 | 0.039 | 0.032 | |||
| 3A | 2221111 | 0.503 | 0.424 | 0.740 | 0.015 | 0.062 |
| 3B | 1211211 | 0.238 | 0.283 | |||
| 3C | 1111211 | 0.131 | 0.160 | |||
| 3D | 1212211 | 0.066 | 0.087 | |||
| 4A | 12 | 0.784 | 0.739 | |||
| 4B | 21 | 0.192 | 0.246 | 0.862 | 0.046 | 0.092 |
| 5A | 1112222 | 0.561 | 0.522 | |||
| 5B | 1121111 | 0.137 | 0.162 | |||
| 5C | 1221111 | 0.145 | 0.134 | |||
| 5D | 2121111 | 0.114 | 0.141 |
*
P- value was calculated for each individual haplotype.