Table 4.
Multivariate analysis of 611 cases (18 were left out due to missing values) treated at least 24 hours, odds ratio for death or other unfavourable (transfer out, default, physician's decision to stop early) outcomes. Reference category is favourable treatment outcome
Variable | Death | Other unfavourable | |||||
N | OR (95% CI) | p | N | OR (95% CI) | p | ||
Sex | female | 34 | 1 | 28 | 1 | ||
male | 68 | 2.51 (1.42–4.45) | 0.002 | 48 | 1.47 (0.83–2.61) | 0.18 | |
Age at diagnosis | risk per five years | 102 | 1.29 (1.16–1.42) | <0.001 | 76 | 0.96 (0.88–1.041) | 0.29 |
Immunosuppression | no | 74 | 1 | 72 | 1 | ||
yes | 28 | 2.11 (1.12–3.97) | 0.020 | 4 | 0.32 (0.097–1.062) | 0.063 | |
TB history | no | 96 | 1 | 73 | 1 | ||
yes | 6 | 0.36 (0.133–0.97) | 0.044 | 3 | 0.32 (0.087–1.16) | 0.082 | |
Specialty responsible for ending treatment | pulmonary | 58 | 1 | 67 | 1 | ||
internal medicine | 16 | 14.08 (4.76–41.66) | <0.001 | 4 | 6.89 (1.66–28.59) | 0.008 | |
general medicine | 22 | 6.24 (3.00–12.98) | <0.001 | 4 | 2.11 (0.65–6.86) | 0.21 | |
other | 6 | 4.72 (1.46–15.33) | 0.010 | 1 | 0.58 (0.060–5.68) | 0.64 | |
Pause of treatment | no | 86 | 1 | 36 | 1 | ||
yes | 16 | 0.69 (0.33–1.47) | 0.34 | 40 | 3.46 (1.92–6.27) | <0.001 | |
Treatment group | standard treatment A | 60 | 1 | 23 | 1 | ||
standard treatment B | 7 | 0.85 (0.30–2.42) | 0.76 | 19 | 5.92 (2.61–13.44) | <0.001 | |
standard treatment C | 1 | 0.146 (0.017–1.22) | 0.076 | 6 | 1.41 (0.48–4.12) | 0.53 | |
standard treatment D | 24 | 1.42 (0.76–2.67) | 0.28 | 15 | 0.94 (0.45–1.95) | 0.86 | |
other combination | 8 | 1.15 (0.43–3.07) | 0.79 | 11 | 1.54 (0.63–3.75) | 0.34 | |
ineffective | 2 | 2.64 (0.29–24.38) | 0.39 | 2 | 3.54 (0.49–25.30) | 0.21 |
Significant p-values are darkened.