Table 3.
Genetic diversity of E1/E2 quasispecies from plasma, LVP and liver in patient as determined by E1 and HVR1 nucleotide substitution analysis.
Compartments | E1/E2
|
HVR1
|
||||
---|---|---|---|---|---|---|
dN | dS | dN/dS | dN | dS | dN/dS | |
Plasma | 0.036 (0.036) | 0.045 (0.029) | 0.79 | 0.144 (0.177) | 0.051 (0.058) | 2.80 |
LVP | 0.038 (0.041) | 0.066 (0.049) | 0.59 | 0.173 (0.193) | 0.135 (0.100) | 1.28 |
Liver | 0.017 (0.025) | 0.025 (0.032) | 0.69 | 0.082 (0.113) | 0.027 (0.069) | 3.02 |
dN and dS, mean and standard deviation (in brackets) of proportions of nonsynonymous substitutions per nonsynonymous sites and synonymous substitutions per synonymous sites.