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Comparison of phenotypes in PA-deficient mice, Pank2-deficient mice, and human patients with PKAN
| Phenotype | PA-deficient diet | Pank2 mice | PKAN patients |
|---|---|---|---|
| Movement disorder | + | − | + |
| Retinal degeneration | N/A | + | + |
| Azoospermia | + | + | ? |
| Eye and skin lesions | + | − | − |
| Premature greying | + | − | − |
| Growth retardation | + | + | − |
