Table 1.
Differentially expressed proteins in HPV-16 E6 expressing keratinocytes
| Name | LocusLink ID | SwissProt ID | Fold changes (E6/Y54D) |
|---|---|---|---|
| Cdk1/Cdc2 | 983 | P06493 | * |
| MCM6 | 4175 | Q14566 | * |
| Beclin | 8678 | Q14457 | 3.43 |
| FEN-1 | 2237 | P39749 | 3.33 |
| Flotillin-1 | 14251 | O08917 | 3.29 |
| FADD | 8772 | Q13158 | 3.00 |
| PI3-Kinase C2 β | 5287 | O00750 | 2.96 |
| Cyclin A | 890 | P20248 | 2.66 |
| Jun | 16476 | P05627 | 2.64 |
| DNA Polymerase ε cat. | 5426 | Q07864 | 2.64 |
| Nestin | 10763 | P21263 | 2.64 |
| Karyopherin β 2 | 3838 | P52292 | 2.63 |
| PBK | 55872 | Q9NPD9 | 2.60 |
| GS15 | 54400 | O35152 | 2.58 |
| Cip1/WAF1 | 1026 | P38936 | 2.51 |
| Dystrobrevin | 13527 | Q9D2N4 | 2.50 |
| V-1/myotrophin | 94351 | P80144 | 2.46 |
| Glutamine Synthetase | 2752 | P15104 | 2.45 |
| Ron alpha | 4486 | Q04912 | 2.36 |
| Glucocorticoid R | 2908 | P04150 | 2.24 |
| Eg5 | 3832 | P52732 | 2.24 |
| p38 delta/SAPK4 | 5603 | O15264 | 2.16 |
| Na,K ATPase β 2 | 482 | P14415 | 2.14 |
| Plakophilin 2a | 5318 | Q99959 | 2.12 |
| FBP | 8880 | Q96AE4 | 2.10 |
| DRBP76 | 3609 | Q12906 | 2.01 |
| p160 | 10514 | O35851 | 0.50 |
| basic FGF-21kD | 2246 | P09038 | 0.49 |
| p115 | 56042 | P41542 | 0.48 |
| p53 | 7157 | P13481 | 0.45 |
| Vesl-1L | 65137 | O88800 | 0.45 |
| L-Caldesmon | 800 | Q05682 | 0.41 |
| p140mDia | 13367 | O08808 | 0.37 |
| hILP/XIAP | 331 | P98170 | 0.27 |
Proteins with more than 2-fold changes and statistically significant differences on the steady-state level between NIKS-E6 cells and NIKS-Y54D cells.
*
, represents presence of a protein in NIKS-E6 cells versus an absence in NIKS-Y54D cells of a protein.