TABLE 2.
Half-life of Pub1 mRNA targets
| Strain | Half-life of targeta:
|
||||
|---|---|---|---|---|---|
| RPS16B | GCN4 | RPL17A | RPS24B | WSC3 | |
| Wild type | 19.8 ± 2.1 | 14.4 ± 1.6 | >20 | >20 | 19.4 ± 0.9 |
| Δpub1 | 6.0 ± 0.5 | 6.5 ± 0.8 | 7.6 ± 1.2 | 8.1 ± 0.9 | 11.6 ± 3.1 |
| nab2-1 | 9.2 ± 1.5 | 16.0 ± 2.8 | 12.5 ± 0.6 | 14.0 ± 0.4 | >20 |
| Δpub1 nab2-1 | 4.6 ± 0.3 | 9.0 ± 1.9 | ND | ND | ND |
| nab2-67 | 8.3 ± 0.5 | 15.1 ± 2.1 | 11.6 ± 0.9 | 15.3 ± 1.1 | >20 |
| Δpub1 nab2-67 | 6.9 ± 0.6 | 7.1 ± 1.2 | ND | ND | ND |
| rat7-1 | 18.7 ± 1.8 | 13.2 ± 1.7 | ND | ND | ND |
| Δpub1 Δupf1 | 5.6 ± 0.5 | 13.9 ± 1.4 | ND | ND | ND |
| nab2-1 Δupf1 | 8.5 ± 1.3 | 15.3 ± 2.5 | ND | ND | ND |
| nab2-67 Δupf1 | 9.1 ± 1.2 | 14.5 ± 2.1 | ND | ND | ND |
a
ND, not determined.