. 2007 Sep 26;6:132. doi: 10.1186/1475-2875-6-132

Table 1.

Main characteristics of the area and intervention in Ifakara and Manhiça

	Ifakara	Manhiça
Years of intervention	1999–2001	2002–2004
Number of children randomized	701	1503
Incidence of malaria in placebo group^a	0.36	0.43
EIR*	29	38
Transmission	Perennial	Perennial with marked seasonality
IPTi regimen**	2, 3, 9	3, 4, 9
Iron supplementation**	2–6	-
1st line Malaria Treatment during study	SP	SP + AQ
ITN use	68%	0
HIV seroprevalence (at ANC)	6.7%	19%
Hb AS prevalence ***	12%	0
SP parasitological sensitivity#	69% (62/90)	78.6% (55/70)
SP ACR#	94% (84/89)	83% (67/81)

*EIR = Entomological inoculation rate

**months of age

*** hemoglobin AS genotype

# at day 14. ACR = adequate clinical response

^aepisode/child/year