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. 2007 Jul 3;9(3):3.

Table 1.

Clinical and Histopathologic Categorization of Nasopharyngeal Carcinoma Cases

Clinical Staging Histopathologic Typing
Stage II 8 (26.7%) WHO type 1 9 (30%)
Stage III 12 (40%) WHO type 2 6 (30%)
Stage IV 10 (33.3%) WHO type 3 51 (50%)

Stage II (T2N0M0)

Stage III (T3N0M0-T1,2 or3,N1M0)

Stage IV (T4N0M0-any T,N2 or N3,.M0-any T, any N,M1)

T1: Tumor confined to 1 site or no tumor visible

T2: Involving 2 sites (both posterosuperior and lateral wall)

T3: Extension into nasal cavity or oropharynx

T4: Tumor invasion of skull or cranial nerve involvement (or both)

N1: Metastasis in a single ipsilateral lymph node < 3 cm

N2: Metastasis in contralateral, bilateral, multiple lymph nodes or > 3 cm but < 6 cm

N2: Metastasis in lymph nodes > 6 cm

M0: No distant metastasis

M1: Distant metastasis.

WHO type 1: Squamous cell carcinoma

WHO type 2: Nonkeratinizing carcinoma

WHO type 3: Undifferentiated carcinoma that is lymphoepithelioma and anaplastic carcinoma