Table 1.

Pathophysiology of Functional Dyspepsia: Proposed Mechanisms and Related Symptoms

Mechanism	Associated Symptoms
Delayed gastric emptying	Postprandial fullness, nausea, vomiting
Hypersensitivity to gastric distension	Epigastric pain, belching, weight loss
Impaired accommodation	Early satiety, weight loss
Helicobacter pylori infection	Unknown
Duodenal lipid hypersensitivity	Nausea
Duodenal acid hypersensitivity	Nausea
Unsuppressed phasic contractility	Bloating
Esophageal acid sensitivity	Heartburn
Longitudinal esophageal contractions	Chest pain