Table 1.
Demographic and Laboratory Data of All Studied Cases
| Parameters | Controls (n = 15) | CHC Without Cirrhosis (n = 50) | CHC With Cirrhosis (n = 30) | HCC With HCV (n = 30) |
|---|---|---|---|---|
| Age | 42.8±6.6 | 42.4±9.3 | 45.1±5.9 | 48.9±7.2 |
| Male/female ratio | 2/1 | 4/1 | 17/13 | 5/1 |
| Pallor | 0 (0) | 2 (4) | 5 (16.5) | 8 (26.6) |
| Jaundice | 0 (0) | 3 (6) | 6 (20) | 13 (43.3) |
| Palmer erythema | 0 (0) | 0 (0) | 15 (50) | 17 (56.6) |
| Spider nevi | 0 (0) | 0 (0) | 14 (46.6) | 14 (46.6) |
| Lower-limb edema | 0 (0) | 0 (0) | 16 (53.3) | 9 (30) |
| Child-Pugh classification | ||||
| A | 10 (100) | 50 (100) | 8 (26.6) | 1 (3.3) |
| B | 0 (0) | 9 (30) | 11 (36.6) | |
| C | 0 (0) | 13 (43.3) | 18 (60) | |
| AST (U/L) | 8.09 ±2.11 | 14.91±5.32 | 11.42±4.12 | 18.90±6.47 |
| ALT (U/L) | 7.73±2.04 | 15.09±6.80 | 12.18±5.33 | 16.38±6.32 |
| Albumin (g/dL) | 4.01±0.38 | 3.60±0.85 | 3.80±0.72 | 3.08±0.48 |
| PT concentration | 97.6±3.4 | 89.7±5.8 | 41.4±11.2 | 68.5±3.8 |
| Alpha-fetoprotein (IU/mL) | 3.39±2.9 | 9.36±13.6 | 10.41±15.6 | 25.04±27.9 |
Data were expressed as means ± SD or as percent value (%).
Normal range for ALT and AST was up to 12 U/L.
Normal range for albumin was 3.5–5 g/dL.
Normal range of prothrombin concentration was 85%–100%.
Normal range for alpha-fetoprotein was 0.1–9.6 IU/mL.