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. 2007 Dec 1;4(12):e335. doi: 10.1371/journal.pmed.0040335

Figure 2. Pattern of Emergence of N348I Early in Drug Therapy Failure.

Figure 2

The pattern of emergence of N348I relative to key drug resistance mutations in the RT is shown with respect to days post therapy. These patients had neither N348I nor key drug resistance mutations present at baseline. Mixtures of WT and mutants were considered mutant in this analysis. The presence of the indicated key mutations was included from data available from each time point up to the appearance of N348I. If subsequent time points also contained N348I, then the key mutations present at this time point was also included in the analysis.