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. 2007 Dec 4;5(12):e321. doi: 10.1371/journal.pbio.0050321

Figure 2. Incomplete Tutor Song Imitation by FoxP2 Knockdown Pupils.

Figure 2

Each sonogram depicts a typical motif of one animal (scale bars indicate 100 ms, frequency range 0–8,600 Hz). Tutor syllables are underlined with black bars and identified by letters. The identity of pupil syllables was determined by similarity comparison to tutor syllables using SAP software. Imprecisely copied pupil syllables are designated with red italic letters.

(A–C) (A) tutor #38 and shControl-injected pupil, (B) tutor #396 and shFoxP2-injected pupil, and (C) tutor #414 and shFoxP2-injected pupil. ShFoxP2-injected pupils copied fewer syllables and the fidelity of syllable imitation was worse than in shControl pupils, reflected by lower SAP scores (similarity/accuracy indicated vertically at the right edge of the sonograms).

(D) The mean similarity scores between tutor and pupil motifs were significantly lower in shFoxP2- injected pupils than in shControl- and shGFP-injected pupils (± SEM; two-tailed Mann-Whitney U test, **p < 0.001, Bonferroni-corrected α-level). There was no significant difference between shGFP- and shControl-injected animals (not significant [n.s.], p > 0.5).