Table 1. Loci Linked to Mendelian Causes of ALS.
| Gene name | Locus Name | Inheritance Mode | Locus | Selected References |
| Cu/Zn superoxide dismutase (SOD1) | ALS1 | AD | 21q22.1 | 43 |
| ALSIN | ALS2 | AR | 2q33.1 | 40 |
| Senataxin (SETX) | ALS4 | AD | 9q34.13 | 3 |
| Dyncatin (DCTN1) | AD | 2p13 | 4,5 | |
| Angiogenin (ANG) | 14q11.1-q1.2 | 6 | ||
| Microtubule associated protein tau (MAPT)* | AD | 17q21.1 | 45 | |
| ALS3 | AD | 18q21 | 14,41 | |
| ALS5 | AD | 15q15.1-q21.1 | 46 | |
| ALS6 | AD | 16q21 | 10 | |
| ALS7 | AD | 20p13 | 10 | |
| Vesicle associated protein B (VAPB) | ALS8 | AD | 20q13.33 | 11 |
| ALS-FTD | AD | 9q21-22 | 12 | |
| ALS-FTD | AD | 9p13.2-21.3 | 13 |
*
Multi-system neurodegeneration dominated by fronto-temporal dementia.
AD = Autosomal Dominant. AR = Autosomal recessive.