Fig 8.
Role of Rho kinase in S1P-stimulated motility and invasiveness. U-118-control or S1P receptor overexpressing cells were pretreated with or without Y-27632 for 30 minutes and then examined for S1P regulation of cell motility and invasiveness as described for Figure 4. Results are means ± standard deviations of triplicte determinations. The * indicates a statistically significant difference (p < 0.05) for S1P + Y-27632 compared to S1P alone for a given cell line.