Figure 1. CIH increased ROS generation in mouse brain cortical neurons.
A.The experimental profile for primary brain cortical neurons exposed to chronic intermittent hypoxia (NOX: normoxia control; CIH: chronic intermittent hypoxia). B. DCF fluorescent analysis of ROS generation in cortical neurons exposed to CIH (n=3; * indicates significant compared to NOX control, p < 0.05). C. DHE fluorescent analysis of ROS generation in cortical neurons exposed to CIH (n=3; * indicates significant compared to NOX control, p < 0.05). D. Representative spin trapping EPR analysis of ROS generation in cortical neurons exposed to CIH (n=3).