Fig. 1.

Spatial distribution of significant increases in brain activation in men and women when comparing the auditory processing of noise, music, and a baseline. Activations are superimposed on an anatomical MRI template of SPM2. Clusters are significant at p < 0.05 FDR corrected for multiple comparisons. L=left hemisphere, y = −20 and y = −6 means a coronal plane, respectively, 20 mm and 6 mm posterior to the anterior commissure, z = 8 means a horizontal plane 8 mm dorsal to the anterior commissure, z  = −1 means a horizontal plane 1 mm ventral to the anterior commissure. a Contrasting music with noise, women showed activation in the secondary auditory areas only, whereas men showed activation in both PAC and secondary auditory areas. b Comparing music to the baseline, both women and men showed bilateral activation in the PAC and secondary auditory areas. c Comparing noise to the baseline, women showed bilateral activation in the PAC. In men, on the other hand, no significant activation was found. The differences between men and women in a and c are significant (see Table 2)