Figure 1.

Structure and phenotypic effects of constructs expressing modified derivatives of E(spl). The designations of the constructs, the primary structure of the encoded peptide, the number of insertions tested as well as that of lethal insertions, and the effects of these constructs after activation by either sca-Gal4 or ZB1.4 are listed. In most cases, the degree of suppression of bristle development is indicated by ∗ and the intensity of dominant–negative effects by +, ++, +++; 0 = no effect. In the case of scutellar expression of lethal of scute (ZB1.4) simultaneously with E(spl) variants, the average number of bristles per scutellum (±SD) is given. Various defects in bristle differentiation (shorter and/or thinner bristles and split bristles) are indicated as diff. The regions in which double sockets and split bristles were found are indicated.