Granular cast count in a single longitudinal section of the renal outer medulla of male rats (n = 10), following 3-month exposures to d-limonene, decalin, propylene glycol mono-t-butyl ether (PGMBE), and Stoddard solvent IIC (SS IIC). Data are presented as mean ± S.E.; *significantly greater than controls, p ≤ 0.05. Numbers of animals with the lesion are presented in the box insert. Doses or exposures in prechronic studies that were common to those in 2-year studies are indicated by ^.