Figure 3 Mean annual change in FEV₁ in ml/year (with 95% confidence interval) for men and women for low and high mean daily dosage of inhaled corticosteroid use (<720 and ⩾720 μg/day). Corrected for level of FEV₁ at age 30 (centred at 2.8 l), height (centred at 1.75 m), pack years smoking, and oral corticosteroid use. There were significant differences between before and after introduction of inhaled corticosteroids, and between low and high daily dosage of inhaled corticosteroid use in men and women.