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Table 3 Long term analysis: significant prognostic factors for composite event using univariate analysis (ITT population).

Composite event Selected subjects (N = 730) p value*
No (N = 271) Yes (N = 459)
Age (years) 0.072
 <65 155 (40%) 231 (60%) 386
 ⩾65 116 (34%) 228 (71%) 344
Number of AECBs in previous year ⩽0.001
 2–3 220 (42%) 307 (58%) 527
 ⩾4 51 (25%) 152 (75%) 203
Bronchodilators ⩽0.001
 No 247 (40%) 371 (60%) 618
 Yes 24 (21%) 88 (79%) 112

2 test.

The full analysis including non‐significant risk factors is shown in table S4 available online at http://www.thoraxjnl.com/supplemental.