Table 4 Independent prognostic factors for occurrence of the composite event using a stepwise Cox model (ITT population).
| Parameter | Hazard ratio | Probability | 95% Confidence interval | |
|---|---|---|---|---|
| Lower limit | Upper limit | |||
| Treatment (0 = comparator; 1 = moxifloxacin) | 0.816 | 0.031 | 0.678 | 0.982 |
| Age (0 = <65 years; 1 = ⩾ 65 years) | 1.219 | 0.039 | 1.010 | 1.470 |
| FEV1 (%) at enrolment (0 = ⩾50; 1 = <50) | 1.265 | 0.014 | 1.048 | 1.526 |
| Number of previous AECBs (0 = 2–3; 1 = ⩾4) | 1.631 | <0.001 | 1.338 | 1.988 |
| Bronchodilators (0 = no; 1 = yes) | 1.477 | 0.001 | 1.166 | 1.872 |
There was no interaction between treatment and any of the individual factors (age, p = 0.080; FEV1, p = 0.505; number of previous AECBs, p = 0.247; acute bronchodilators, p = 0.752).