Figure 2. SDS-PAGE and immunoblot analysis of purified recombinant TH and native proPO.
Recombinant TH was analyzed by Coomassie staining (0.5 μg, lane 1) or detection with anti-TH antiserum (10 ng, lane 5). The predicted mass of the monomer form of rTH is 66.3 kDa. 2 μg proPO was analyzed by Coomassie staining (lane 3) or detection with anti-proPO antiserum (lane 4) or anti-TH antiserum (lane 5). ProPO subunits 1 and 2, which have predicted masses of 79 and 80 kDa, respectively, were partially resolved. Note that no TH was detected in the proPO fraction. Molecular mass standards (in kDa) are indicated to the left of each lane.