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Episome-based gene expression in HT-1376 (A), Hep G2 (B), and RAJI (C). Cells were cotransfected with pRSVlacZII and either pRC/CMV.107/402-T (solid bars) or pRC/CMV (open bars). Shown are representative results from at least two separate experiments. Significance was determined using an unpaired, one-tailed Student’s t test. ∗, P < 0.0001; ∗∗, P = 0.0001.
