Table 2.
Replication activity of 107/402-T-based episomes in human and animal cell lines
| Species | Cell Line | Type | Copy number per cell* |
|---|---|---|---|
| Human | HT-1376 | Bladder | 1,400 |
| 5637 | Bladder | 100,000 | |
| MCF-7 | Breast | 8,600 | |
| T98G | Brain | 25,000 | |
| SW480 | Colon | 78 | |
| Hs68 | Fibroblast | 82 | |
| Hep G2 | Hepatoma | 25,000 | |
| NCI-H69 | Lung | 9,000 | |
| NCI-H82 | Lung | 1,200 | |
| NCI-H146 | Lung | 2,200 | |
| RAJI | Lymphoma | 7,000 | |
| Simian | CV-1 | Kidney | 11,000 |
| Dog | MDCK-2 | Kidney | <1 |
| D17 | Osteosarcoma | <1 | |
| Hamster | BHK | Kidney | <1 |
| V79 | Lung | 35 | |
| Rat | PC12 | Pheochromocytoma | <1 |
| Mouse | F9 | Embryonal carcinoma | <1 |
| 3T3 | Fibroblast | <1 |
*
Peak copy number was achieved between days 2 and 6.